ATP synthase inhibition, an overlooked confounding factor in the mitochondrial stress test.

The mitochondrial stress test, a widely used procedure to study energy metabolism using extracellular flux analysis, involves the inhibition of ATP synthase (a.k.a. complex V [CV]). This inhibition was recently shown to cause a glycolysis-dependent underestimation of two key mitochondrial respiratio...

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Bibliographic Details
Main Authors: Jesse Corbin, Eric A Lehoux, Isabelle Catelas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0328256
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