Promising markers of CIMP+ colon tumors identified on the basis of TCGA data analysis

Promising markers of CIMP+ colon tumors identified on the basis of TCGA data analysis

CIMP+ (CpG­Island Methylator Phenotype) tumors are characterized by dense methylation of promoter CpG islands of many genes at once and represent a separate group of malignant neoplasms of the colon. Despite the fact that the diagnostics of CIMP+ tumors has a significant prognostic value, an effecti...

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Bibliographic Details
Main Authors: G. S. Krasnov, A. D. Beniaminov, R. A. Tychko, G. A. Puzanov, R. O. Novakovskiy, A. V. Kudryavtseva, A. A. Dmitriev
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2018-01-01
Series:Вавиловский журнал генетики и селекции
Subjects:
colon cancer
cimp+
epigenetics
dna methylation
tcga
quantitative pcr
molecular markers
Online Access:https://vavilov.elpub.ru/jour/article/view/1268
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