H2A.Z primes an epigenetic landscape for memory CD8+ T cell recall response

H2A.Z primes an epigenetic landscape for memory CD8+ T cell recall response

Abstract The rapid recall ability is a hallmark of memory CD8+ T cells, but the underlying mechanisms remain incompletely understood. Here we find that histone variant H2A.Z is expressed at higher levels in memory CD8+ T cells than in naïve cells. Furthermore, in memory CD8+ T cells H2A.Z is deposit...

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Main Authors: Wei Liang, Jiyu Ding, Qian Chai, Mengjie Lv, Shuting Zheng, Xiangxiang Cao, Zhimin Wang, Xiaoling Ying, Wenqi Wu, Guohong Li, Mingzhao Zhu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62976-4
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https://doi.org/10.1038/s41467-025-62976-4

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