Acetylcholine modulates prefrontal outcome coding during threat learning under uncertainty

Outcomes can vary even when choices are repeated. Such ambiguity necessitates adjusting how much to learn from each outcome by tracking its variability. The medial prefrontal cortex (mPFC) has been reported to signal the expected outcome and its discrepancy from the actual outcome (prediction error)...

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Bibliographic Details
Main Authors: Gaqi Tu, Peiying Wen, Adel Halawa, Kaori Takehara-Nishiuchi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/102986
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