In knee osteoarthritis, the production of cytokines and metalloproteinases in presence of chondrocytes and CD4+ T cells depends on T cell subset: An in vitro analysis

Objective: Osteoarthritis (OA) is driven by biomechanical and biochemical inflammatory processes, including CD4+ T cell infiltration and activation. However, the role of CD4+ T cell subsets interacting with neighboring cells shaping the local inflammatory milieu have remained largely unexplored. Thi...

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Bibliographic Details
Main Authors: H. Platzer, M. Wellbrock, G. Pourbozorg, R. Mayakrishnan, S. Gantz, B. Khamees, S. Maciej, B. Moradi
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Osteoarthritis and Cartilage Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2665913125000780
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