ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks.

Chromosome rearrangements can form when incorrect ends are matched during end joining (EJ) repair of multiple chromosomal double-strand breaks (DSBs). We tested whether the ATM kinase limits chromosome rearrangements via suppressing incorrect end utilization during EJ repair of multiple DSBs. For th...

Full description

Saved in:
Bibliographic Details
Main Authors: Nicole Bennardo, Jeremy M Stark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001194&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!