Oral squamous cell carcinoma vs. medication-related osteonecrosis of the jaw in patients assuming bone-modifying agents: a diagnostic challenge in a multi-hospital case series

Oral squamous cell carcinoma vs. medication-related osteonecrosis of the jaw in patients assuming bone-modifying agents: a diagnostic challenge in a multi-hospital case series

BackgroundDespite advances in the diagnosis of oral squamous cell carcinoma (OSCC), most cases are diagnosed in advanced stages, influencing negatively the patient's prognosis. The absence of specific signs and symptoms contributes to the diagnostic delay of OSCC, often leading to confusion wit...

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Bibliographic Details
Main Authors: Rodolfo Mauceri, Martina Coppini, Gaetano La Mantia, Giuseppe Seminara, Mario Pérez-Sayáns, Corrado Toro, Rita Vitagliano, Hitoshi Kawamata, Toshiki Hyodo, Giuseppe Colella, Vito Rodolico, Giuseppina Campisi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oral Health
Subjects:
oral squamous cell carcinoma (OSCC)
squamous cell carcinoma of head and neck
oral cancer
medication-related osteonecrosis of the jaw (MRONJ)
osteonecrosis of the jaw (ONJ)
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2025.1574425/full
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https://www.frontiersin.org/articles/10.3389/froh.2025.1574425/full

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