A functional screen uncovers circular RNAs regulating excitatory synaptogenesis in hippocampal neurons

Abstract Circular RNAs (circRNAs) are an expanding class of largely unexplored RNAs which are prominently enriched in the mammalian brain. Here, we systematically interrogate their role in excitatory synaptogenesis of rat hippocampal neurons using RNA interference. Thereby, we identify seven circRNA...

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Bibliographic Details
Main Authors: Darren Kelly, Silvia Bicker, Jochen Winterer, Prakruti Nanda, Pierre-Luc Germain, Christoph Dieterich, Gerhard Schratt
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58070-4
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