A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes.

Human African Trypanosomiasis is a vector-borne disease of sub-Saharan Africa that causes significant morbidity and mortality. Current therapies have many drawbacks, and there is an urgent need for new, better medicines. Ideally such new treatments should be fast-acting cidal agents that cure the di...

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Bibliographic Details
Main Authors: Manu De Rycker, Sandra O'Neill, Dhananjay Joshi, Lorna Campbell, David W Gray, Alan H Fairlamb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001932&type=printable
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