Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells

Silencing ZIC5 suppresses glycolysis and promotes disulfidptosis in lung adenocarcinoma cells

Objective This study aims to explore the effects of silencing Zic family member 5 (ZIC5) on glucose metabolism and disulfidptosis in lung adenocarcinoma (LUAD) cells.Methods Data from The Cancer Genome Atlas (TCGA) was used to analyze ZIC5 expression in LUAD and its association with patient outcomes...

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Bibliographic Details
Main Authors: Cimei Zeng, Denggao Huang, Lei Wang, Haimei Liang, Ximiao Ma
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Cancer Biology & Therapy
Subjects:
Lung adenocarcinoma
ZIC5
glycolysis
glucose metabolism
disulfidptosis
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2025.2501780
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https://www.tandfonline.com/doi/10.1080/15384047.2025.2501780

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