Defense arsenal of the strict anaerobe Clostridioides difficile against reactive oxygen species encountered during its infection cycle

Defense arsenal of the strict anaerobe Clostridioides difficile against reactive oxygen species encountered during its infection cycle

ABSTRACT Clostridioides difficile, a strict anaerobe, is the major cause of antibiotic-associated diarrhea. This enteropathogen must adapt to oxidative stress mediated by reactive oxygen species (ROS), notably those released by the neutrophils and macrophages recruited to the site of infection or th...

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Bibliographic Details
Main Authors: Aurélie Lotoux, Léo Caulat, Catarina Martins Alves, Carolina Alves Feliciano, Claire Morvan, Filipe Folgosa, Isabelle Martin-Verstraete
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mBio
Subjects:
peroxidase
superoxide reductase
rubrerythrin
stress response
PerR
Sigma B
Online Access:https://journals.asm.org/doi/10.1128/mbio.03753-24
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https://journals.asm.org/doi/10.1128/mbio.03753-24

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