Pharmacologic and genetic evidence converge on mechanisms of psychotic illness

Abstract Idiopathic and substance-induced forms of psychotic illness afflict millions of people worldwide, and it is largely unknown whether these two forms emerge through the same molecular mechanisms. Though genetic studies have implicated thousands of genes in idiopathic psychotic illnesses (e.g....

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Bibliographic Details
Main Authors: Brian Fennessy, Liam Cotter, Nicole W. Simons, Lora E. Liharska, Girish N. Nadkarni, Douglas M. Ruderfer, Alexander W. Charney
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03456-7
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