An Integration of RNA Sequencing and Network Pharmacology Approaches Predicts the Molecular Mechanisms of the Huo-Xue-Shen Formula in the Treatment of Liver Fibrosis

An Integration of RNA Sequencing and Network Pharmacology Approaches Predicts the Molecular Mechanisms of the Huo-Xue-Shen Formula in the Treatment of Liver Fibrosis

<b>Background</b>: Liver fibrosis is a prevalent, chronic inflammatory condition characterized by the excessive accumulation of extracellular matrix components and, primarily, collagen in the liver. Huo-xue-shen (HXS) has proven effective for the treatment of liver fibrosis. However, the...

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Bibliographic Details
Main Authors: Keying Jiang, Jianfeng Bao, Zhonghan Lou, Fei Liu, Keyang Xu, Hiu Yee Kwan
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
Huo-xue-shen
liver fibrosis
machine learning
molecular docking
network pharmacology
Online Access:https://www.mdpi.com/1424-8247/18/2/227
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