AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Abstract Adeno‐associated virus (AAV) vectors are a leading platform for gene therapy. Recently, AAV‐mediated gene therapy in the inner ear has progressed from laboratory use to clinical trials, but the lower transduction rates in outer hair cells (OHCs) in the organ of Corti and in vestibular hair...

Full description

Saved in:
Bibliographic Details
Main Authors: Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202408873
Tags: Add Tag
No Tags, Be the first to tag this record!