Proteinuria and Progression of Renal Damage: The Main Pathogenetic Mechanisms and Pharmacological Approach

Proteinuria and Progression of Renal Damage: The Main Pathogenetic Mechanisms and Pharmacological Approach

The integrity of the glomerular filtration barrier maintains protein excretion below 150 mg/day. When urinary proteins increase, this indicates damage to the filtration barrier. However, proteinuria is not only a marker of kidney damage but also exacerbates it through various mechanisms involving th...

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Bibliographic Details
Main Authors: Elisa Longhitano, Vincenzo Calabrese, Chiara Casuscelli, Silvia Di Carlo, Salvatore Maltese, Adolfo Romeo, Massimo Calanna, Giovanni Conti, Domenico Santoro
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Medicina
Subjects:
proteinuria
CKD
ACEi
ARBs
finerenone
sparsentan
Online Access:https://www.mdpi.com/1648-9144/60/11/1821
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