Novel protocatechuic acid encapsulated bovine serum albumin functionalized folic acid nanoparticles for targeted therapy in urethane-induced lung cancer model

Novel protocatechuic acid encapsulated bovine serum albumin functionalized folic acid nanoparticles for targeted therapy in urethane-induced lung cancer model

Abstract Lung cancer mortality rates are rising globally, increasing the need for innovative, natural compounds with fewer side effects. Protocatechuic acid (PCA) is a natural phenolic compound with cytotoxic effects against human lung cancer cells, but its poor water solubility limits its use. We h...

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Bibliographic Details
Main Authors: Alaa I. Ibrahim, Heba A. Sahyon, Adel M. Attia, Ashraf A. El-Shehawy
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Protocatechuic acid
Albumin nanoparticles
CD44
NF-kB
FAK
MAPK
Online Access:https://doi.org/10.1038/s41598-025-08465-6
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https://doi.org/10.1038/s41598-025-08465-6

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