Cryptic absence and genetic variation of Plasmodium falciparum PfHRP2 and PfHRP3 from isolates in Papua, Indonesia

Cryptic absence and genetic variation of Plasmodium falciparum PfHRP2 and PfHRP3 from isolates in Papua, Indonesia

Abstract The rising prevalence of histidine-rich protein 2 (PfHRP2) gene deletions (pfhrp2-) poses a threat to the accuracy of PfHRP2-based rapid diagnostic tests (RDTs). However, evidence of this deletion is scarce in Indonesia. We examined the prevalence of pfhrp2 and its paralogue histidine-rich...

Full description

Saved in:
Bibliographic Details
Main Authors: Agatha Mia Puspitasari, Edwin Sutanto, Khilal Syauqi, Ristya Amalia, Fahira Ainun Nisa, Leily Trianty, Elizabeth Sidhartha, Enny Kenangalem, Jeanne Rini Poespoprodjo, Rukhsana Ahmed, Ewurama Owusu, Lise Carlier, Kevin K. A. Tetteh, Qin Cheng, Rintis Noviyanti
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Plasmodium falciparum
RDT
pfhrp2
pfhrp3
Sequence variation
Papua
Online Access:https://doi.org/10.1038/s41598-025-02834-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-02834-x

Similar Items