SYNTHESIS, PHYSICO-CHEMICAL ANALYSIS AND PHARMACOLOGICAL ACTIVITY OF SOME DERIVATIVES OF WARFARIN

Methods of synthesis of 7 warfarin derivatives from which three are combined has been developed. Their structural features, physicochemical properties of synthesized compounds by modern and spectral methods (IR, NMR spectroscopy) were determined. Their anticoagulant activity in vivo were studied by...

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Bibliographic Details
Main Authors: A. Z. Abyshev, I. K. Zhurkovich, D. Yu. Ivkin, C. B. Nguyen
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/429
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