Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases

The spectrum of vascular lesions developing in breast or chest wall skin following lumpectomy or mastectomy and radiation is wide and ranges from atypical vascular lesions with a benign clinical behaviour to frankly malignant, angiosarcoma ranging histologically from well to poorly differentiated va...

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Main Authors: P. S. Jayalakshmy, Aswathy P. Sivaram, Joy Augustine, P. Bindu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2012/710318
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author P. S. Jayalakshmy
Aswathy P. Sivaram
Joy Augustine
P. Bindu
author_facet P. S. Jayalakshmy
Aswathy P. Sivaram
Joy Augustine
P. Bindu
author_sort P. S. Jayalakshmy
collection DOAJ
description The spectrum of vascular lesions developing in breast or chest wall skin following lumpectomy or mastectomy and radiation is wide and ranges from atypical vascular lesions with a benign clinical behaviour to frankly malignant, angiosarcoma ranging histologically from well to poorly differentiated variety. Postmastectomy-postirradiation atypical vascular lesions (AVLs) are rare and develop in the skin adjacent to the mastectomy scar. About hundred cases have been reported in the literature so far. AVLs have also been reported in patients after breast conservation surgery within the breast parenchyma or in the skin around the scar. The incidence appears to be rising. The exact reason for this is not known. The newer modalities of radiation therapy may be contributory to the pathogenesis. More studies have to be done in this area to prove the causal relationship. We are reporting the cases of 2 patients with carcinoma of breast who developed postmastectomy-postirradiation atypical vascular lesions. The cases were received in our department within a 6-month period.
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spelling doaj-art-50c3be3971f145e3a74cb75928581bf82025-02-03T01:26:01ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/710318710318Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 CasesP. S. Jayalakshmy0Aswathy P. Sivaram1Joy Augustine2P. Bindu3Department of Pathology, Government Medical College, Kerala, Thrissur 680596, IndiaDepartment of Pathology, Government Medical College, Kerala, Thrissur 680596, IndiaDepartment of Pathology, Government Medical College, Kerala, Thrissur 680596, IndiaDepartment of Pathology, Government Medical College, Kerala, Thrissur 680596, IndiaThe spectrum of vascular lesions developing in breast or chest wall skin following lumpectomy or mastectomy and radiation is wide and ranges from atypical vascular lesions with a benign clinical behaviour to frankly malignant, angiosarcoma ranging histologically from well to poorly differentiated variety. Postmastectomy-postirradiation atypical vascular lesions (AVLs) are rare and develop in the skin adjacent to the mastectomy scar. About hundred cases have been reported in the literature so far. AVLs have also been reported in patients after breast conservation surgery within the breast parenchyma or in the skin around the scar. The incidence appears to be rising. The exact reason for this is not known. The newer modalities of radiation therapy may be contributory to the pathogenesis. More studies have to be done in this area to prove the causal relationship. We are reporting the cases of 2 patients with carcinoma of breast who developed postmastectomy-postirradiation atypical vascular lesions. The cases were received in our department within a 6-month period.http://dx.doi.org/10.1155/2012/710318
spellingShingle P. S. Jayalakshmy
Aswathy P. Sivaram
Joy Augustine
P. Bindu
Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
Case Reports in Pathology
title Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
title_full Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
title_fullStr Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
title_full_unstemmed Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
title_short Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
title_sort postmastectomy postirradiation atypical vascular lesion of the skin report of 2 cases
url http://dx.doi.org/10.1155/2012/710318
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