Sex hormone-binding globulin promotes the osteogenic differentiation potential of equine adipose-derived stromal cells by activating the BMP signaling pathway

Sex hormone-binding globulin promotes the osteogenic differentiation potential of equine adipose-derived stromal cells by activating the BMP signaling pathway

BackgroundMusculoskeletal injuries and chronic degenerative diseases pose significant challenges in equine health, impacting performance and overall well-being. Sex Hormone-Binding Globulin (SHBG) is a glycoprotein determining the bioavailability of sex hormones in the bloodstream, and exerting crit...

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Bibliographic Details
Main Authors: Jennifer M. Irwin-Huston, Lynda Bourebaba, Nabila Bourebaba, Artur Tomal, Krzysztof Marycz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Endocrinology
Subjects:
osteogenesis
ASCs
SHBG
BMP
mitochondrial dynamics
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1424873/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1424873/full

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