Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect

Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect

Background Low-dose radiotherapy (RT) is a promising treatment likely to increase the efficacy of immunotherapy, including programmed cell death ligand 1 (PD-L1) blockade, in cancer therapy. Further exploration and optimization of such combinatorial strategies are required. Notably, the ability of l...

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Main Authors: Pierre-Antoine Laurent, Eric Deutsch, Charlotte Robert, Antonin Levy, Michele Mondini, Marine Gerbé De Thoré, Winchygn Liu, Lydia Meziani, Céline Clémenson, Flavie Naulin, Liu Shi, Lisa Bouarroudj, Nathan Benzazon, Marine Aglave, Paul Bergeron, Lisa Sitterlé, Daphné Morel
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/6/e011487.full
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https://jitc.bmj.com/content/13/6/e011487.full

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