Two Novel Single-Chain Variable Fragments, EB211 and EB279, Exert Antibacterial Activity Against Acinetobacter baumannii by Destabilizing the Outer Membrane

Two Novel Single-Chain Variable Fragments, EB211 and EB279, Exert Antibacterial Activity Against Acinetobacter baumannii by Destabilizing the Outer Membrane

Introduction: Acinetobacter baumannii is notorious for its high resistance levels, and the development of clinically effective antimicrobial agents is an urgent medical challenge. Single-chain variable fragments (scFvs) that exhibit antibacterial properties against challenging pathogens, such as...

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Bibliographic Details
Main Authors: Eilnaz Basardeh1, Farzaneh Nazari1, Abolfazl Fateh1, Seyed Davar Siadat1, Akbar Oghalaie2, Masoumeh Azizi3, Fatemeh Rahimi-Jamnani1*
Format: Article
Language:English
Published: Pasteur Institute of Iran 2024-12-01
Series:Journal of Medical Microbiology and Infectious Diseases
Subjects:
acinetobacter baumannii
antibacterial agents
monoclonal antibodies
single-chain nariable fragments
magnesium
Online Access:https://jommid.pasteur.ac.ir/article-1-678-en.html
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