Immunogenicity of ARCT-154, a self-amplifying mRNA COVID-19 vaccine, in different booster settings

Immunogenicity of ARCT-154, a self-amplifying mRNA COVID-19 vaccine, in different booster settings

A self-amplifying mRNA (sa-mRNA) vaccine against COVID-19 (ARCT-154) was evaluated for immunogenicity in three clinical studies with four booster scenarios: first homologous booster, first heterologous booster, second heterologous booster, and a two-dose series in previously infected participants. N...

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Main Authors: Yoshiaki Oda, Nhan Thi Ho, Xuan-Hung Nguyen, Ly-Thi-Le Tran, Van Thu Nguyen, Yasuhiro Iwama, Iori Okura, Yukihiro Yagi, Jenny Guek-Hong Low, Steven G. Hughes, Roberto Bugarini, Rose Sekulovich, Hongfan Jin, Carole Verhoeven, Igor Smolenov
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Vaccine: X
Subjects:
(1–7): COVID-19 disease
Self-amplifying mRNA
Booster
Immunogenicity
Safety
Online Access:http://www.sciencedirect.com/science/article/pii/S2590136225000877
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http://www.sciencedirect.com/science/article/pii/S2590136225000877

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