Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer

Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer

ObjectiveGastric cancer is a harmful disease, the comorbidity mechanism and causality relationship between this disease and other diseases are worth studying.MethodsUsing a two-sample Mendelian Randomization method, this study revealed the potential causal effect of atrial fibrillation (AF) on gastr...

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Bibliographic Details
Main Authors: Zhao Sicheng, Zhang Jingcheng, Zhang Shuo, Lou Jiaheng, Cai Yan, Bai Xing, Jiang Tao, Zhang Guangji
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Genetics
Subjects:
atrial fibrillation
gastric cancer
genetic instrument
mendelian randomization
single-cell sequencing
fibroblasts
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1446661/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1446661/full

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