Evaluation of transduction efficiency in pancreatic beta and alpha cells utilizing various AAV serotypes

Abstract Adeno-associated viruses (AAVs) have emerged as powerful tools for delivering genes to various cell types, including pancreatic endocrine cells. Currently, AAV serotype 8 (AAV8) is the primary AAV vector employed for transducing pancreatic cells for transgene expression. We aimed to determi...

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Bibliographic Details
Main Authors: Vishal Ahuja, Sanjeev Jeyabalan, Emmanuel S. Tzanakakis
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-05518-8
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