Dual Upcycling of Olive Leaves for the Biocatalytic Synthesis of Antioxidant Cortisone Derivatives

Dual Upcycling of Olive Leaves for the Biocatalytic Synthesis of Antioxidant Cortisone Derivatives

Bioconversion of cortisone leads to the synthesis of the steroid derivatives 1,9β,17,21-tetrahydroxy-4-methyl-19-nor-9β-pregna-1,3,5(10)-trien-11,20-dione (SCA) and 1,9β,17,20β,21-pentahydroxy-4-methyl-19-nor-9β-pregna-1,3,5(10)-trien-11-one (SCB), which have been identified as biologically active m...

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Bibliographic Details
Main Authors: Filippo Marchetti, Irene Gugel, Stefania Costa, Ilenia Gugel, Anna Baldisserotto, Erika Baldini, Stefano Manfredini, Silvia Vertuani
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antioxidants
Subjects:
olive leaves
upcycling
circular economy
cortisone
steroids
biocatalysis
Online Access:https://www.mdpi.com/2076-3921/14/7/821
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