Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC

IntroductionSmall cell lung cancer (SCLC) is characterized by significant heterogeneity and plasticity, contributing to its aggressive progression and therapy resistance. Autophagy, a conserved cellular process, is implicated in many cancers, but its role in SCLC remains unclear.MethodsUsing a genet...

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Bibliographic Details
Main Authors: Yujie Hao, Mingchen Li, Wenxu Liu, Zhenyi Ma, Zhe Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1509183/full
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