The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.

The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.

With the exception of ApoE4, genome-wide association studies have failed to identify strong genetic risk factors for late-onset Alzheimer's disease, despite strong evidence of heritability, suggesting that many low penetrance genes may be involved. Additionally, the nature of the identified gen...

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Main Authors: Sharon C Yates, Amen Zafar, Erzsebet M Rabai, James B Foxall, Sheila Nagy, Karen E Morrison, Carl Clarke, Margaret M Esiri, Sharon Christie, A David Smith, Zsuzsanna Nagy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114050
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https://doi.org/10.1371/journal.pone.0114050

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