Metformin as antiviral therapy protects hyperglycemic and diabetic patients

Metformin as antiviral therapy protects hyperglycemic and diabetic patients

ABSTRACT Viral infections disrupt glucose metabolism; however, their impact on disease prognosis in highly pathogenic viruses remains largely unknown. There is an additional need to investigate the antiviral mechanisms of glucose-lowering therapeutics. Here, our multicenter clinical study shows that...

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Main Authors: Xi Wang, Xiaojie Zheng, Honghan Ge, Ning Cui, Ling Lin, Ming Yue, Chuanlong Zhu, Qi Zhou, Peixin Song, Xing Shang, Rui Wang, Zhen Wang, Zhiyou Wang, Yunfa Zhang, Xiaohong Yin, Linsheng Yang, Hong Su, Hao Li, Wei Liu
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
Subjects:
severe fever with thrombocytopenia syndrome virus
hyperglycemia
diabetes
metformin
antiviral therapy
Online Access:https://journals.asm.org/doi/10.1128/mbio.00634-25
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https://journals.asm.org/doi/10.1128/mbio.00634-25

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