STING exerts antiviral innate immune response by activating pentose phosphate pathway

STING exerts antiviral innate immune response by activating pentose phosphate pathway

Abstract Background The innate immune system serves as the host’s first line of defense against invading pathogens. Stimulator of interferon genes (STING) is a key component of this system, yet its relationship with glucose metabolism, particularly in antiviral immunity, remains underexplored. Metho...

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Main Authors: Dan-Hui Wu, Zi-Long Zhao, Wei-Tao Yin, Huai Liu, Xiong-Yan Xiang, Ling-Jun Zhu, Jun-Qi Li, Zhen-Hua Yan, Yu-Jia Li, Yong-Ping Jian, Zhi-Xiang Xu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
STING
PPP
Transketolase
Antiviral immune response
Inflammatory factors
Online Access:https://doi.org/10.1186/s12964-024-01983-2
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https://doi.org/10.1186/s12964-024-01983-2

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