Development and characterization of high-efficiency cell-adapted live attenuated vaccine candidate against African swine fever

Development and characterization of high-efficiency cell-adapted live attenuated vaccine candidate against African swine fever

African swine fever (ASF), a contagious and lethal haemorrhagic disease of domestic pigs and wild boars, poses a significant threat to the global pig industry. Although experimental vaccine candidates derived from naturally attenuated, genetically engineered, or cell culture-adapted ASF virus have b...

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Main Authors: Min Ho Kim, Ashan Subasinghe, Yongkwan Kim, Hyeok-Il Kwon, Yehjin Cho, Kiramage Chathuranga, Ji-Won Cha, Ji-Yoon Moon, Ji-Hyeon Hong, Jin Kim, Seung-Chul Lee, Niranjan Dodantenna, Nuwan Gamage, W. A. Gayan Chathuranga, Yeonji Kim, In-Joong Yoon, Joo Young Lee, In Pil Mo, Weonhwa Jheong, Sung-Sik Yoo, Jong-Soo Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
African swine fever, CA-CAS-01-A cell, live-attenuated virus, ASFV-MEC-01, vaccine, Type I IFN, MGF100-1R
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2432372
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https://www.tandfonline.com/doi/10.1080/22221751.2024.2432372

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