Autism spectrum disorder related phenotypes in a mouse model lacking the neuronal actin binding protein profilin 2

IntroductionProfilin 2 (PFN2) is an actin binding protein highly expressed in the brain that participates in actin dynamics. It has been shown in vitro and in vivo that in neurons it functions both post-synaptically to shape and maintain dendritic arborizations and spine density and plasticity, as w...

Full description

Saved in:
Bibliographic Details
Main Authors: Walter Witke, Marina Di Domenico, Laura Maggi, Alessia Di Nardo, Valentin Stein, Pietro Pilo Boyl
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1540989/full
Tags: Add Tag
No Tags, Be the first to tag this record!