A holistic rat model to investigate therapeutic interventions in Parkinson’s disease: viral induction of a slow-progressing motor phenotype, dopaminergic degeneration and early microglia neuroinflammation
Parkinson’s disease is a chronic progressive neurodegenerative disorder, mostly manifesting in late adulthood. Patients suffering from this idiopathic disease of the nervous system develop cardinal motor symptoms that usually appear after non-motor symptoms. It is characterized by loss of dopaminerg...
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| Main Authors: | Ekaterini Kefalakes, Franziska J. Mewes, Diana Peristich, Clara Plötner, Volodymyr Shcherbatyy, Julia Schipke, Friederike Schneider, Christopher Käufer, Regina Rumpel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-10-01
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| Series: | Brain Research Bulletin |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S036192302500276X |
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