Sex-Specific effects of vitamin D on autistic behavior and gastrointestinal symptoms in rats via the regulation of serotonin metabolism

Sex-Specific effects of vitamin D on autistic behavior and gastrointestinal symptoms in rats via the regulation of serotonin metabolism

Abstract Vitamin D (VitD) deficiency (VDD) during prenatal and early brain development may be an environmental risk factor for autism spectrum disorder (ASD). While supplementation with high-dose VitD can improve core ASD symptoms, its mechanism is unclear. In addition, VitD regulates the serotonin...

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Bibliographic Details
Main Authors: Bing Wang, Hanyu Dong, Yang Xue, Miaoshui Bai, Yifan Cui, Tong Zhao, Feiyong Jia
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Autism spectrum disorder
Vitamin D
5-HT
Gastrointestinal function
Online Access:https://doi.org/10.1038/s41598-025-05845-w
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https://doi.org/10.1038/s41598-025-05845-w

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