Dysfunction of Collagen Synthesis and Secretion in Chondrocytes Induced by Wisp3 Mutation

Wisp3 gene mutation was shown to cause spondyloepiphyseal dysplasia tarda with progressive arthropathy (SRDT-PA), but the underlying mechanism is not clear. To clarify this mechanism, we constructed the wild and mutated Wisp3 expression vectors and transfected into human chondrocytes lines C-20/A4;...

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Bibliographic Details
Main Authors: Min Wang, Xiao-Fei Man, Ya-Qing Liu, Er-Yuan Liao, Zhi-Feng Shen, Xiang-Hang Luo, Li-Juan Guo, Xian-Ping Wu, Hou-De Zhou
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/679763
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