Germline variants of the MMR/EPCAM genes in Russian patients with Lynch syndrome

Germline variants of the MMR/EPCAM genes in Russian patients with Lynch syndrome

Objective — Lynch syndrome is the most common hereditary cancer syndrome caused by pathogenic variants in the MMR/EPCAM genes. Our goal was to study the germline variants of these genes in the largest sample of patients with Lynch syndrome in Russia. Methods — The study included data on pathogenic...

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Bibliographic Details
Main Authors: Aleksey S. Tsukanov, Aleksey A. Barinov, Vitaly P. Shubin, Anna N. Loginova, Dmitry Yu. Pikunov, Dmitry G. Shakhmatov, Yuri A. Shelygin, Sergey I. Achkasov
Format: Article
Language:English
Published: Limited liability company «Science and Innovations» (Saratov) 2024-09-01
Series:Russian Open Medical Journal
Subjects:
lynch syndrome
colorectal cancer
microsatellite instability
mmr/epcam genes
Online Access:https://romj.org/node/569
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