A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.

Inferring gene regulatory relationships from observational data is challenging. Manipulation and intervention is often required to unravel causal relationships unambiguously. However, gene copy number changes, as they frequently occur in cancer cells, might be considered natural manipulation experim...

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Bibliographic Details
Main Authors: Richard Newton, Lorenz Wernisch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0105522
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