Contribution of polymorphic variants of the NFKB1 transcription factor gene to the development of multifactorial diseases with an infammatory component

Contribution of polymorphic variants of the NFKB1 transcription factor gene to the development of multifactorial diseases with an infammatory component

NFKB1 — a product of the same-name gene – is a transcription factor that regulates the expression of target genes which encode a wide range of proteins with properties essential for functioning of the body. Numerous studies confrmed the NFKB1 gene's contribution of the polymorphism to the proce...

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Bibliographic Details
Main Authors: A. V. Meyer, T. A. Tolochko, E. A. Astafyeva, M. V. Ulyanova, D. O. Imekina, M. B. Lavryashina
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2022-06-01
Series:Фундаментальная и клиническая медицина
Subjects:
genetic polymorphism
transcription factors
nfkb1
multifactorial diseases
infammation
oncogenesis
Online Access:https://fcm.kemsmu.ru/jour/article/view/555
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