Mechanical signaling regulates vascular smooth muscle cell adaptation in aging

Mechanical signaling regulates vascular smooth muscle cell adaptation in aging

Aging is an independent risk factor for cardiovascular disease. Preventing age-induced arterial dysfunction and the associated risk of cardiovascular disease remains a significant clinical challenge. Aerobic exercise, which induces a temporary increase in both blood flow and pressure in active tissu...

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Bibliographic Details
Main Authors: Amin Mohajeri, Song Yi Shin, Samuel Padgham, Devon J. Boland, Dana Pittman Ratterree, Jacob Blizman, Gang Han, Christopher R. Woodman, Andreea Trache
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Physiology
Subjects:
aging
integrins
actin
mechanical stimulation
vascular smooth muscle
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1593886/full
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https://www.frontiersin.org/articles/10.3389/fphys.2025.1593886/full

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