Sevoflurane inhibition of the developmentally expressed neuronal sodium channel Nav1.3
Abstract Neuronal voltage-gated sodium channels (Nav) are major targets for the neurophysiological actions of general anesthetics. In the adult brain, cell type-specific effects on synaptic transmission are attributed to the differential sensitivity to volatile anesthetics of specific Nav subtypes p...
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| Main Authors: | Jiaxin Xiang, Karl F. Herold, Jimcy Platholi, Hugh C. Hemmings |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-15280-6 |
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