Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.

Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.

Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...

Full description

Saved in:
Bibliographic Details
Main Authors: Marcos Sterkel, Lee R Haines, Aitor Casas-Sánchez, Vincent Owino Adung'a, Raquel J Vionette-Amaral, Shannon Quek, Clair Rose, Mariana Silva Dos Santos, Natalia García Escude, Hanafy M Ismail, Mark I Paine, Seth M Barribeau, Simon Wagstaff, James I MacRae, Daniel Masiga, Laith Yakob, Pedro L Oliveira, Álvaro Acosta-Serrano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000796&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000796&type=printable

Similar Items