Multi-omics analysis identifies SNP-associated immune-related signatures by integrating Mendelian randomization and machine learning in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death globally, characterized by high morbidity and poor prognosis. The complex molecular and immune landscape of HCC makes accurate patient stratification and personalized treatment essential. In this study, we utilized la...

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Bibliographic Details
Main Authors: Qingyan Kou, Zhichao Wu, Wenbin Zhao, Zhenyuan Liu, Shengxian Qiao, Qiang Mu, Xu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-09010-1
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