The Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome

The Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome

Introduction: Metabolic syndrome (MetS) is increasingly recognized as a contributor to kidney disease, yet the underlying mechanisms remain poorly defined. Recent studies suggest a pivotal role for mitochondrial dysfunction in renal injury. We hypothesized that mitochondrial AKT1 signaling in renal...

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Main Authors: Hugo Y.-H. Lin, I-Ya Chen, Tzu-Ming Wang, Chia-Hung Yen, Yumay Chen, Yen-Hua Chen, Dao-Fu Dai, Jee-Fu Huang, Yi-Wen Chiu, Ming-Yu Yang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Kidney International Reports
Subjects:
AKT1 signaling
kidney disease
metabolic syndrome
mitochondrial dysfunction
renal tubular injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924034223
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