Cannabinoid 1 receptor availability in posttraumatic stress disorder: A positron emission tomography study

Abstract The endocannabinoid system (ECS) plays a critical role in fear learning and maintenance and may, therefore, be implicated in the pathophysiology of posttraumatic stress disorder (PTSD). The exact role of cannabinoid receptor 1 (CB1R), a key component of the ECS, remains unclear. Although pr...

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Main Authors: Nachshon Korem, Anahita Bassir Nia, Ansel T. Hillmer, Deepak D’Souza, Nabeel Nabulsi, Jim Ropchan, Yiyun Huang, Kelly Cosgrove, Ifat Levy, Robert H. Pietrzak, Ilan Harpaz-Rotem
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03519-9
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