Collateral sensitivity and cross-resistance in six species of bacteria exposed to six classes of antibiotics

Collateral sensitivity and cross-resistance in six species of bacteria exposed to six classes of antibiotics

ABSTRACT De novo resistance can develop in bacteria as a result of exposure to sublethal concentrations of antibiotics. Once the strain has become resistant to an initial antibiotic, this can cause cross-resistance or collateral sensitivity to a second antimicrobial. Specific collateral sensitivity...

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Bibliographic Details
Main Authors: Xinyu Wang, Luyuan Nong, Gioia Schaar, Belinda Koenders, Martijs Jonker, Wim de Leeuw, Benno H. ter Kuile
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
fusA mutation
collateral sensitivity
cross-resistance
convergent evolution
kanamycin resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00983-25
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https://journals.asm.org/doi/10.1128/spectrum.00983-25

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