Elevated Methylation Contributes to Suppressed Expression of Special AT‐Rich Sequence‐Binding Protein 2 in Colorectal Cancer: A Gene‐Disease Association Study

Elevated Methylation Contributes to Suppressed Expression of Special AT‐Rich Sequence‐Binding Protein 2 in Colorectal Cancer: A Gene‐Disease Association Study

ABSTRACT Background and Aims Special AT‐rich sequence‐binding protein 2 (SATB2) is a commonly used clinical marker for colorectal cancer (CRC) diagnosis. It has been reported that SATB2 expression is significantly downregulated in CRC tissues; however, the underlying mechanism remains unclear. Methy...

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Bibliographic Details
Main Authors: Weitong Cui, Cong Lu, Huaru Xue, Lei Wei, Shuai Li, Lianzheng Su, Dianfang Wei, Xiaoyu Feng, Kai Wang, Chao Song
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Health Science Reports
Subjects:
colorectal cancer
expression
methylation
promoter
SATB2
Online Access:https://doi.org/10.1002/hsr2.71056
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https://doi.org/10.1002/hsr2.71056

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