Histiocyte predominant myocarditis resulting from the addition of interferon gamma to cyclophosphamide-based lymphodepletion for adoptive cellular therapy

Histiocyte predominant myocarditis resulting from the addition of interferon gamma to cyclophosphamide-based lymphodepletion for adoptive cellular therapy

Background Adoptive cellular therapy (ACT) is a promising treatment for synovial sarcoma (SS) with reported response rates of over 50%. However, more work is needed to obtain deeper and more durable responses. SS has a ‘cold’ tumor immune microenvironment with low levels of major histocompatibility...

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Bibliographic Details
Main Authors: Cassian Yee, Seth M Pollack, Robin L Jones, Jianhong Cao, Ernest U Conrad, Stanley R Riddell, Brett A Schroeder, Ralph Graeme Black, Sydney Spadinger, Shihong Zhang, Karan Kohli, Jose G Mantilla
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000247.full
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https://jitc.bmj.com/content/8/1/e000247.full

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