Cardiomyocytes in Hypoxia: Cellular Responses and Implications for Cell-Based Cardiac Regenerative Therapies

Myocardial infarction (MI) is a severe hypoxic event, resulting in the loss of up to one billion cardiomyocytes (CMs). Due to the limited intrinsic regenerative capacity of the heart, cell-based regenerative therapies, which feature the implantation of stem cell-derived cardiomyocytes (SC-CMs) into...

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Bibliographic Details
Main Authors: Kiera D. Dwyer, Caroline A. Snyder, Kareen L. K. Coulombe
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Bioengineering
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Online Access:https://www.mdpi.com/2306-5354/12/2/154
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