Anti-Interleukin-1 Agents in Adult Onset Still's Disease

Interleukin 1β (IL-1β) is emerging as a master mediator of adult onset Still’s disease (AOSD) pathogenesis. This pleiotropic cytokine, whose expression is under the control of the inflammasome pathway, has a wide type of effects. As a key mediator of innate immunity is a potent pyrogen and facilitat...

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Bibliographic Details
Main Authors: Cecilia Giampietro, Bruno Fautrel
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/317820
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