Reconstructing the regulatory programs underlying the phenotypic plasticity of neural cancers

Abstract Nervous system cancers exhibit diverse transcriptional cell states influenced by normal development, injury response, and growth. However, the understanding of these states’ regulation and pharmacological relevance remains limited. Here we present “single-cell regulatory-driven clustering”...

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Bibliographic Details
Main Authors: Ida Larsson, Felix Held, Gergana Popova, Alper Koc, Soumi Kundu, Rebecka Jörnsten, Sven Nelander
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53954-3
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